Calm and processing has me revaluating paper of last post in various ways.

First, all animals are gonadectomized without resupplementation, so even vast activational sex effects would simply be missed.

Second, it has no causality aspect. It highlights what happens somewhere downstream of stress and demonstrates organization/chromosomal neuroinflammation divergence there. But this may just tell us that such factors influence stress-related damage repair, and might tell us nothing about the actual mechanisms underlying MDD mental phenotype. If that is more individually variable than damage repair cascades are, makes sense it is also not seen in their readout.

So in principle, no reason for me to worry so over it.